Keyboard preferences are accessed by going to Word's Tools menu, selecting Cite While You Write Preferences, and clicking the Keyboard tab. From the EndNote tab, select Preferences and then click the Keyboard tab. See the default settings at CWYW Keyboard Commands.
To add or change a keyboard shortcut:
Under "Press New Shortcut Key," enter the new shortcut key combination on the keyboard.
Keyboard shortcuts work in both EndNote and Word.
Click Assign to assign the new shortcut.
To remove an assigned shortcut key, click Remove.
To reset to the defaults, click Reset All to remove custom key assignments.